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A global event challenging the agricultural behemoth Monsanto’s efforts to dominate the world food supply is taking place across the globe as millions of anti-GMO activists join forces against the biotech giant. More than 400 cities will march against Monsanto.

The march against the US chemical and agricultural company Monsanto is an effort to boycott the use of Genetically Modified Organisms in food production.

Marches were planned in 52 countries in addition to some 47 US states that are jointing in the protest.

“MAM supports a sustainable food production system. We must act now to stop GMOs and harmful pesticides,” said Tami Monroe Canal , founder of March Against Monsanto (MAM) in a press release ahead of the global event.

The movement was formed after the 2012 California Proposition 37 on mandatory labeling of genetically engineered food initiative failed, prompting activists to demand a boycott of the GMO in food production.

“Monsanto’s predatory business and corporate agriculture practices threaten their generation’s health, fertility and longevity,” Canal said.

The main aim of the activism is to organize global awareness for the need to protect food supply, local farms and environment. It seeks to promote organic solutions, while “exposing cronyism between big business and the government.”

Activists claim that Monsanto spent hundreds of millions of dollars to “obstruct all labeling attempts” while suppressing all “research containing results not in their favor.”

Birth defects, organ damage, infant mortality, sterility and increased cancer risks are just some of the side-effects GMO is believed to cause.

“That is what the scientists have learned about, that the genetically modified foods will increase allergies that they are going to be less nutritious and that they can possibly or very contain toxins that can make us ill,” Organic Consumers Association’s political director Alexis Baden-Mayer said.