This study from Morocco shows that sub-chronic and chronic exposure to glyphosate in mice, leads to changed the gut microbiota abundance and composition and thus to despair behavior.

Glyphosate based- herbicide exposure affects gut microbiota, anxiety and depression-like behaviors in mice

Full Study: www.sciencedirect.com

Recently, a number of studies have demonstrated the profound relationship between gut microbiota (GM) alterations and behavioral changes. Glyphosate-based herbicides (GBH) have been shown to induce behavioral impairments, and it is possible that they mediate the effects through an altered GM. In this study, we investigated the toxic effects of GBH on GM and its subsequent effects on the neurobehavioral functions in mice following acute, subchronic and chronic exposure to 250 or 500 mg/kg/day.

The effect of these acute and repeated treatments was assessed at the behavioral level using the open field, the elevated plus maze, the tail suspension and splash tests. Then, mice were sacrificed and the intestinal samples were collected for GM analysis.