Massachusetts is the healthiest state, while Mississippi ranks last.

Massachusetts is the healthiest state in which to live this year, according to a new report from the United Health Foundation.

The report ranks states on 35 factors that impact health, from vaccination levels and infant mortality rates to environmental pollution and poverty levels. The analysis also pinpoints public health challenges nationwide.

One particularly troubling trend: The rate of premature death rose for the third year in a row. That’s a sharp reversal from the 20 percent decline in premature deaths seen from 1990 to 2015. And in the past two years, rates of cardiovascular and drug deaths have also climbed.

Here’s a rundown of the report’s findings:

Massachusetts is this year’s healthiest state, followed by Hawaii, Vermont, Utah, and Connecticut.

Mississippi was at the bottom of the rankings, with Louisiana, Arkansas, Alabama, and West Virginia also in the bottom five. Mississippi and Louisiana struggle particularly with high rates of poverty among kids, smoking, and obesity.