This 25 minute video explains in detail the mechanisms of action for mRNA COVID-19 vaccines, as well as highlighting some of the known risks. If you wish to have a better understanding of the technology or wish for a refresher on the tech, as well as to learn a bit of cellular and molecular biology – this is a great primer. So, sit back, relax and open your mind to a bit of science.

The abstract of the paper first mentions that in early clinical trials, SARS-CoV-2 neutralizing antibodies were correlated with protection against infection and disease caused by early viral variants, but not mentioned by the authors – this correlation has not been demonstrated with the various Omicron variants.

The authors of this current work, which focuses on the Pfizer/BioNTech vaccine, note that in studies carried out by Moderna, there is an observed decrease in neutralizing antibody titers in the vaccinated population which corresponds to a decrease in vaccine efficacy against polymerase chain reaction–confirmed Omicron infection in Denmark and symptomatic Omicron infection in the United Kingdom.