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Study Is Largest To Compare Natural and Vaccine-Induced Immunity

A new retrospective observational study conducted by researchers at Tel Aviv University and Maccabi Healthcare in Israel found that unvaccinated individuals who developed an infection with the SARS-CoV-2 virus were considerably more protected against the Delta variant of the virus than those who had received two doses of the Pfizer/BioNTech’s experimental messenger RNA (mRNA) biologic BNT162b2.1 2 3 4 5 6 7 8

According to the study, those who had been vaccinated with BNT162b2 were 13 times more likely to be infected with the Delta variant than those who had already been infected with the SARS-CoV-2 virus and had developed natural immunity to the virus. The study also found that vaccinated individuals were at a significantly higher risk of developing COVID-19 symptoms and being hospitalized for the illness than those with natural immunity.1 2 3 58