According to the Credit Suisse Research Institute’s 2013 study1 “Sugar: Consumption at a Crossroads,” as much as 40 percent of US healthcare expenditures are for diseases directly related to the overconsumption of sugar.

Incredibly, we spend more than $1 trillion each year fighting the damaging health effects of sugar, which runs the gamut from obesity and diabetes, to heart disease and cancer.

The fact that sugar and obesity are linked to an increased risk of cancer is now becoming well-recognized. According to a report² on the global cancer burden, published in 2014, obesity is responsible for an estimated 500,000 cancer cases worldwide each year.

Nearly two-thirds of obesity-related cancers — which include colon, rectum, ovary, and womb cancers — occur in North America and Europe.³ A more recent British report estimates obesity may result in an additional 670,000 cancer cases in the UK alone over the next 20 years.

According to BBC News,⁴ the Cancer Research UK and the UK Health Forum report are calling for a ban on junk food ads aired before 9pm to address out of control rise in obesity and obesity-related diseases.

Meanwhile, a German investigation into diet-induced diseases and related treatment costs reveal that sugar-induced oral disease represents the greatest chunk of that nation’s health care costs.

As noted by the Dental Tribune:⁵

“… [T]he substantial impact of sugar consumption found in the study was mainly due to the costs of treating caries and other diseases of the hard tissue of teeth, hypertensive and cardiovascular diseases, diabetes mellitus, rectal and colon cancer, as well as chronic kidney disease.”

How Excess Sugar and Obesity Promotes Cancer

One of the key mechanisms by which sugar promotes cancer and other chronic disease is through mitochondrial dysfunction.

Since sugar is not our ideal fuel, it burns dirty with far more reactive oxygen species than fat, which generates far more free radicals which in turn causes mitochondrial and nuclear DNA damage along with cell membrane and protein impairment.

Research⁶ has also shown that chronic overeating in general has a similar effect. Most people who overeat also tend to eat a lot of sugar-laden foods — a double-whammy in terms of cancer risk.

Chronic overeating places stress on the endoplasmic reticulum (ER), the membranous network found inside the mitochondria of your cells. When the ER receives more nutrients than it can process, it signals the cell to dampen the sensitivity of the insulin receptors on the surface of the cell.
Thus continuously eating more than your body really needs promotes insulin resistance by the mere fact that your cells are stressed by the work placed on them by the excess nutrients. Insulin resistance in turn is at the heart of most chronic disease, including cancer.