A new study published Monday in Scientific Reports, an online, open access journal from the publishers of Nature, has shown that the glyphosate-based Roundup herbicide causes non-alcoholic fatty liver disease in rats at very low doses.
The new peer-reviewed study led by Dr. Michael Antoniou at King’s College London using cutting edge profiling methods describes the molecular composition of the livers of female rats administered with an extremely low dose of Roundup weed-killer over a 2-year period. The dose of glyphosate from the Roundup administered was thousands of times below what is permitted by regulators worldwide. The study revealed that these animals suffered from non-alcoholic fatty liver disease (NAFLD).
This study is unique in that it is the first to show a causative link between consumption of Roundup at a real-world environmental dose and a serious disease condition.
From an article in Sustainable Pulse:
Dr. Antoniou stated Monday; “The findings of our study are very worrying as they demonstrate for the first time a causative link between an environmentally relevant level of Roundup consumption over the long-term and a serious disease – namely non-alcoholic fatty liver disease. Our results also suggest that regulators should reconsider the safety evaluation of glyphosate-based herbicides.
Regulators worldwide accept toxicity studies in rats as indicators of human health risks. Therefore, the results of this latest study may have serious consequences for human health.
NAFLD currently affects 25 percent of the US population. Risk factors include being overweight or obese, having diabetes, high cholesterol or high triglycerides in the blood. Rapid weight loss and poor eating habits also may lead to NAFLD. However, some people develop NAFLD even if they do not have any risk factors. Symptoms include fatigue, weakness, weight loss, loss of appetite, nausea, abdominal pain, spider-like blood vessels, yellowing of the skin and eyes (jaundice), itching, fluid build-up and swelling of the legs (edema) and abdomen (ascites), and mental confusion. NAFLD can progress to the more serious condition non-alcoholic steatohepatitis (NASH).
The U.S. Environmental Protection Agency (EPA), which was supposed to finish its 15-year review of glyphosate more than a year ago, and rule on whether to reregister it or ban it, is still twiddling its thumbs. The U.S. Food & Drug Administration won’t test foods for glyphosate residue. Meanwhile, in the EU, where the European Commission has also failed to act, citizens are taking matters into their own hands—by launching a European Citizens Initiative (ECI) inviting the Commission “to propose to Member States a ban on glyphosate, to reform the pesticide approval procedure, and to set EU-wide mandatory reduction targets for pesticide use.”
Full study here