Profile of the Gene Giants--The World's Five
Largest Genetic Engineering Companies

7 January 2000
RAFI Geno-Types

WARNING: The information that appears below will expire faster than a
Flavr Savr tomato. The table is merely a snapshot as of 7 January 2000,
based on pro forma sales for announced mergers. Given current consolidation
trends, this information will be out-dated soon. Please stay tuned for
further updates.

**AgBiotech's Five Jumbo Gene Giants**
Just Five Survive Consolidation Squeeze

Company Global Rankings by Sector
(in US$ millions - based on 1998 revenues)

AVENTIS = Hoechst + Rhone Poulenc (France)
Agrochemical Ranking: # 2 -- $4,675
Seed Ranking: not ranked - $134 million
Pharmaceutical Ranking: # 2 -- $13,650 (combined sales of Hoechst Marion
Roussel and Rhone-Poulenc Rorer)

MONSANTO (USA) + PHARMACIA & UPJOHN (pending - not finalized)
Agrochemical Ranking: # 3 -- $4,030
Seed Ranking: # 2 -- $1,800
Pharmaceutical Ranking: # 9 -- $9,000 (combined sales of Pharmacia &
Upjohn + Searle)

Agrochemical Ranking: # 4 -- $3,155
Seed Ranking: # 1 -- $1,835
Pharmaceutical Ranking: # 42 -- $1,109

SYNGENTA * = Novartis + AstraZeneca (pending - not finalized)
Agrochemical Ranking: # 1 -- $7,050
Seed Ranking: # 3 -- $1,000
Pharmaceutical Ranking: (pharma companies did not merge)
# 4 AstraZeneca $12,750
# 7 Novartis $11,175

Agrochemical Ranking: # 7 -- $2,130
Seed Ranking: not ranked - $162 million
Pharmaceutical Ranking: N/A

If announced mergers are consummated, five Jumbo Gene Giants will control
68% of the global agrochemical market and over 20% of the commercial seed
trade worldwide.

Notes: The announced merger between Novartis + AstraZeneca is pending - not
final. The pharmaceutical divisions of the two companies did not merge.
The pharma ranking of each company is given separately, for comparative

The announced merger between Monsanto + Pharmacia & Upjohn is pending - not

Sources: Information based on RAFI research, AGROW agrochemical rankings
and SCRIP Pharmaceutical League Table, December, 1999.

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